Aging exacerbates depressive-like behavior in mice in response to activation of the peripheral innate immune system

Jonathan P. Godbout, Maïté Moreau, Jacques Lestage, Jing Chen, Nathan L. Sparkman, Jason O'Connor, Nathalie Castanon, Keith W. Kelley, Robert Dantzer, Rodney W. Johnson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)2341-2351
Number of pages11
JournalNeuropsychopharmacology
Volume33
Issue number10
DOIs
StatePublished - Sep 2008
Externally publishedYes

ASJC Scopus Subject Areas

  • Pharmacology
  • Psychiatry and Mental health

Keywords

  • Aging
  • Behavior
  • Cytokines
  • Depression
  • Lipopolysaccharide
  • Serotonin

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