Fiber-optic Singlet Oxygen [1 O2 ( 1 Dg)] Generator Device Serving as a Point Selective Sterilizer

David Aebisher; Matibur Zamadar; Adaikapillaic Mahendran; Goutam Ghosh; Cathy McEntee; Alexander Greer

Fiber-optic Singlet Oxygen [1 O2 ( 1 Dg)] Generator Device Serving as a Point Selective Sterilizer

David Aebisher, Matibur Zamadar, Adaikapillaic Mahendran, Goutam Ghosh, Cathy McEntee, Alexander Greer

Chemistry and Biochemistry

Research output: Contribution to journal › Article

Abstract

Traditionally, Type II heterogeneous photo-oxidations produce singlet oxygen via external irradiation of a sensitizer and external supply of ground-state oxygen. A potential improvement is reported here. A hollow-core fiber-optic device was developed with an ‘‘internal’’ supply of light and flowing oxygen, and a porous photosensitizer-end capped configuration. Singlet oxygen was delivered through the fiber tip. The singlet oxygen steady-state concentration in the immediate vicinity of the probe tip was ca 20 fM by N-benzoyl-DL-methionine trapping. The device is portable and the singlet oxygen-generating tip is maneuverable, which opened the door to simple disinfectant studies. Complete Escherichia coli inactivation was observed in 2 h when the singlet oxygen sensitizing probe tip was immersed in 0.1 mL aqueous samples of 0.1–4.4 · 107 cells. Photobleaching of the probe tip occurred after ca 12 h of use, requiring baking and sensitizer reloading steps for reuse.

Original language	Undefined/Unknown
Journal	Faculty Publications
State	Published - Jan 1 2010

Access to Document

http://scholarworks.sfasu.edu/chemistry_facultypubs/26

Cite this

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title = "Fiber-optic Singlet Oxygen [1 O2 ( 1 Dg)] Generator Device Serving as a Point Selective Sterilizer",

abstract = "Traditionally, Type II heterogeneous photo-oxidations produce singlet oxygen via external irradiation of a sensitizer and external supply of ground-state oxygen. A potential improvement is reported here. A hollow-core fiber-optic device was developed with an {\textquoteleft}{\textquoteleft}internal{\textquoteright}{\textquoteright} supply of light and flowing oxygen, and a porous photosensitizer-end capped configuration. Singlet oxygen was delivered through the fiber tip. The singlet oxygen steady-state concentration in the immediate vicinity of the probe tip was ca 20 fM by N-benzoyl-DL-methionine trapping. The device is portable and the singlet oxygen-generating tip is maneuverable, which opened the door to simple disinfectant studies. Complete Escherichia coli inactivation was observed in 2 h when the singlet oxygen sensitizing probe tip was immersed in 0.1 mL aqueous samples of 0.1–4.4 · 107 cells. Photobleaching of the probe tip occurred after ca 12 h of use, requiring baking and sensitizer reloading steps for reuse.",

author = "David Aebisher and Matibur Zamadar and Adaikapillaic Mahendran and Goutam Ghosh and Cathy McEntee and Alexander Greer",

year = "2010",

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TY - JOUR

T1 - Fiber-optic Singlet Oxygen [1 O2 ( 1 Dg)] Generator Device Serving as a Point Selective Sterilizer

AU - Aebisher, David

AU - Zamadar, Matibur

AU - Mahendran, Adaikapillaic

AU - Ghosh, Goutam

AU - McEntee, Cathy

AU - Greer, Alexander

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Traditionally, Type II heterogeneous photo-oxidations produce singlet oxygen via external irradiation of a sensitizer and external supply of ground-state oxygen. A potential improvement is reported here. A hollow-core fiber-optic device was developed with an ‘‘internal’’ supply of light and flowing oxygen, and a porous photosensitizer-end capped configuration. Singlet oxygen was delivered through the fiber tip. The singlet oxygen steady-state concentration in the immediate vicinity of the probe tip was ca 20 fM by N-benzoyl-DL-methionine trapping. The device is portable and the singlet oxygen-generating tip is maneuverable, which opened the door to simple disinfectant studies. Complete Escherichia coli inactivation was observed in 2 h when the singlet oxygen sensitizing probe tip was immersed in 0.1 mL aqueous samples of 0.1–4.4 · 107 cells. Photobleaching of the probe tip occurred after ca 12 h of use, requiring baking and sensitizer reloading steps for reuse.

AB - Traditionally, Type II heterogeneous photo-oxidations produce singlet oxygen via external irradiation of a sensitizer and external supply of ground-state oxygen. A potential improvement is reported here. A hollow-core fiber-optic device was developed with an ‘‘internal’’ supply of light and flowing oxygen, and a porous photosensitizer-end capped configuration. Singlet oxygen was delivered through the fiber tip. The singlet oxygen steady-state concentration in the immediate vicinity of the probe tip was ca 20 fM by N-benzoyl-DL-methionine trapping. The device is portable and the singlet oxygen-generating tip is maneuverable, which opened the door to simple disinfectant studies. Complete Escherichia coli inactivation was observed in 2 h when the singlet oxygen sensitizing probe tip was immersed in 0.1 mL aqueous samples of 0.1–4.4 · 107 cells. Photobleaching of the probe tip occurred after ca 12 h of use, requiring baking and sensitizer reloading steps for reuse.

M3 - Article

JO - Faculty Publications

JF - Faculty Publications

ER -