Palladium and Iron Cocatalyzed Aerobic Alkene Aminoboration

Aminoboration of simple alkenes with nitrogen nucleophiles is a challenge in synthetic chemistry. Although palladium can catalyze this transformation, it faces stability issues. A new method using a combination of palladium and iron as cocatalysts has been developed to address this. The iron cocatalyst plays a key role in achieving the desired reaction and in regenerating the palladium catalyst. This method has been successfully demonstrated on various alkenes and nitrogen nucleophiles.