Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system

Jing Chen; Jessica B. Buchanan; Nathan L. Sparkman; Jonathan P. Godbout; Gregory G. Freund; Rodney W. Johnson

doi:10.1016/j.bbi.2007.08.014

Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system

Jing Chen, Jessica B. Buchanan, Nathan L. Sparkman, Jonathan P. Godbout, Gregory G. Freund, Rodney W. Johnson

Producción científica: Article › revisión exhaustiva

Idioma original	English
Páginas (desde-hasta)	301-311
Número de páginas	11
Publicación	Brain, Behavior, and Immunity
Volumen	22
N.º	3
DOI	https://doi.org/10.1016/j.bbi.2007.08.014
Estado	Published - mar 2008
Publicado de forma externa	Sí

ASJC Scopus Subject Areas

Immunology
Endocrine and Autonomic Systems
Behavioral Neuroscience

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10.1016/j.bbi.2007.08.014

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title = "Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system",

keywords = "Aging, Hippocampus, Interleukin-1, Laser capture microdissection, Lipopolysaccharide, Working memory",

author = "Jing Chen and Buchanan, {Jessica B.} and Sparkman, {Nathan L.} and Godbout, {Jonathan P.} and Freund, {Gregory G.} and Johnson, {Rodney W.}",

note = "Funding Information: We thank Dr. James Zachary for assisting with LCM and Dr. Masaaki Nakai (University of Illinois) for helping with IHC staining. Dr. Colm Cunningham at University of Southampton (U.K.) also provided helpful advice on IHC staining. This research was supported by NIH grants AG16710 (R.W.J.), AG023580 (R.W.J.), MH069148 (R.W.J.) and DK64862 (G.G.F.). J.B.B. and J.P.G. were supported by a Ruth L. Kirchstein NRSA Postdoctoral Fellowship.",

year = "2008",

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doi = "10.1016/j.bbi.2007.08.014",

language = "English",

volume = "22",

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T1 - Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system

AU - Chen, Jing

AU - Buchanan, Jessica B.

AU - Sparkman, Nathan L.

AU - Godbout, Jonathan P.

AU - Freund, Gregory G.

AU - Johnson, Rodney W.

N1 - Funding Information: We thank Dr. James Zachary for assisting with LCM and Dr. Masaaki Nakai (University of Illinois) for helping with IHC staining. Dr. Colm Cunningham at University of Southampton (U.K.) also provided helpful advice on IHC staining. This research was supported by NIH grants AG16710 (R.W.J.), AG023580 (R.W.J.), MH069148 (R.W.J.) and DK64862 (G.G.F.). J.B.B. and J.P.G. were supported by a Ruth L. Kirchstein NRSA Postdoctoral Fellowship.

PY - 2008/3

Y1 - 2008/3

KW - Aging

KW - Hippocampus

KW - Interleukin-1

KW - Laser capture microdissection

KW - Lipopolysaccharide

KW - Working memory

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DO - 10.1016/j.bbi.2007.08.014

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EP - 311

JO - Brain, Behavior, and Immunity

JF - Brain, Behavior, and Immunity

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